Simplicity in biology

Un article en fichier joint de Uri Alon paru dans le Magazine Nature en mars 2007.

Uri Alon
Departments of Molecular Cell Biology and Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel.
Abstract :
Networks of interactions between thousands of molecules within cells seem to defy comprehension, but shared principles of design may simplify the picture. 'Complex' is perhaps the most common adjective used to describe biological phenomena. In every cell, complex networks of interactions occur between thousands of metabolites, proteins and DNA.
 

Extraits :
“…Biological networks seem to be built, to a good approximation, from only a few types of patterns called network motifs”…”The same small set of network motifs, discovered in bacteria, have been found in gene-regulation networks across diverse organisms, including plants and animals. Evolution seems to have ‘rediscovered’ the same motifs again and again in different systems…”

Confirme par une autre approche la grande idée de Simon Conway Morris : la convergence (et donc la canalisation) de l’évolution. Retrouve aussi la conclusion de l’article 5) sur les structures de base existantes dans la nature.

Se trouve sur :
http://www.nature.com/nature/journal/v446/n7135/full/446497a.html